Satoshi Kubota Selected Research

Connective Tissue Growth Factor

1/2017	In Vivo Evaluation of Cartilage Regenerative Effects of CCN2 Protein.
6/2012	Role of LRP1 in transport of CCN2 protein in chondrocytes.
8/2011	Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice.
2/2011	Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-acting element of structure-anchored repression in ccn2 mRNA.
7/2008	Clinical significance and pathogenic function of connective tissue growth factor (CTGF/CCN2) in osteolytic mandibular squamous cell carcinoma.
4/2008	Plasma connective tissue growth factor is a novel potential biomarker of cardiac dysfunction in patients with chronic heart failure.
5/2007	Increased connective tissue growth factor relative to brain natriuretic peptide as a determinant of myocardial fibrosis.
3/2007	Different transcriptional strategies for ccn2/ctgf gene induction between human chondrocytic and breast cancer cell lines.
7/2006	Pathogenic role of connective tissue growth factor (CTGF/CCN2) in osteolytic metastasis of breast cancer.
8/2004	Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor).

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Satoshi Kubota Research Topics

Disease

14	Neoplasms (Cancer) 04/2021 - 03/2003
5	Neoplasm Metastasis (Metastasis) 04/2021 - 07/2006
5	Osteoarthritis 09/2017 - 08/2004
5	Hypertrophy 01/2017 - 01/2003
5	Chondrosarcoma 02/2011 - 12/2002
4	Inflammation (Inflammations) 05/2022 - 04/2005
4	Hypoxia (Hypoxemia) 01/2020 - 05/2002
4	Breast Neoplasms (Breast Cancer) 01/2020 - 05/2002
4	Fibrosis (Cirrhosis) 01/2016 - 05/2007
3	Carcinoma (Carcinomatosis) 04/2021 - 10/2003
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 03/2019 - 08/2016
2	Body Weight (Weight, Body) 12/2021 - 10/2019
2	Wounds and Injuries (Trauma) 03/2019 - 10/2003
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2018 - 07/2008
2	Rheumatoid Arthritis 01/2005 - 10/2003
1	Wilms Tumor (Wilm's Tumor) 12/2021
1	Insulin Resistance 09/2021
1	B-Cell Leukemia (Leukemia, B Cell) 01/2021
1	Lymphoma (Lymphomas) 01/2021
1	Triple Negative Breast Neoplasms 01/2021
1	Orthostatic Hypotension (Postural Hypotension) 01/2021
1	Hypotension (Low Blood Pressure) 01/2021
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2020
1	Stomatitis 11/2018
1	Pain (Aches) 11/2018
1	Mucinous Adenocarcinoma (Mucinous Carcinoma) 11/2018
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 11/2018
1	Small Cell Carcinoma 11/2018
1	Starvation 03/2018
1	Fever (Fevers) 01/2018
1	Abdominal Pain (Pain, Abdominal) 01/2018
1	Stomach Neoplasms (Stomach Cancer) 11/2017
1	Margins of Excision 10/2017
1	Genomic Instability 01/2017
1	Uterine Cervical Dysplasia 08/2016
1	Papillomavirus Infections 08/2016
1	Endometrioid Carcinoma 04/2016
1	Endometrial Neoplasms (Endometrial Cancer) 04/2016

Drug/Important Bio-Agent (IBA)

13	Connective Tissue Growth FactorIBA 01/2017 - 05/2002
11	Proteins (Proteins, Gene)FDA Link 12/2021 - 05/2002
7	Messenger RNA (mRNA)IBA 12/2021 - 05/2002
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2017 - 03/2003
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2015 - 10/2003
4	CytokinesIBA 02/2015 - 01/2005
3	EnzymesIBA 01/2020 - 10/2003
3	Matrix Metalloproteinases (MMPs)IBA 01/2020 - 05/2002
3	Biological ProductsIBA 03/2019 - 05/2009
3	Biomarkers (Surrogate Marker)IBA 11/2018 - 04/2008
2	AntigensIBA 01/2005 - 10/2003
1	RNA (Ribonucleic Acid)IBA 05/2022
1	Interleukin-17 ReceptorsIBA 05/2022
1	InterleukinsIBA 05/2022
1	Insulin-Like Growth Factor I (IGF-1)IBA 12/2021
1	Growth Hormone (Somatotropin)IBA 12/2021
1	Insulin (Novolin)FDA Link 09/2021
1	AdipokinesIBA 09/2021
1	Histidine (L-Histidine)FDA Link 09/2021
1	Alanine (L-Alanine)FDA Link 09/2021
1	Carbonated WaterIBA 01/2021
1	Drinking WaterIBA 01/2021
1	Antineoplastic Agents (Antineoplastics)IBA 01/2021
1	APTO-253IBA 01/2021
1	SynaptophysinIBA 01/2020
1	Chromogranin AIBA 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2020
1	XanthineIBA 10/2019
1	HypoxanthineIBA 10/2019
1	Dihydrotachysterol (AT 10)IBA 10/2019
1	Adenine FDA LinkGeneric 10/2019
1	CalpainIBA 10/2019
1	Adenylosuccinate LyaseIBA 10/2019
1	purineIBA 10/2019
1	GuanineIBA 10/2019
1	Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA 10/2019
1	Aggrecans (Aggrecan)IBA 03/2019
1	Small Leucine-Rich ProteoglycansIBA 03/2019
1	Fibronectins (Fibronectin)IBA 03/2019
1	chordinIBA 03/2019
1	Retinaldehyde (Retinal)IBA 03/2019
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 11/2018
1	Glucose (Dextrose)FDA LinkGeneric 03/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2018
1	Long Noncoding RNAIBA 01/2018
1	Irinotecan (Camptosar)FDA LinkGeneric 11/2017
1	Fibroblast Growth Factor 1 (FGF-1)IBA 09/2017
1	Papillomavirus Vaccines (HPV Vaccines)IBA 10/2016
1	Pharmaceutical PreparationsIBA 04/2016
1	Everolimus FDA Link 04/2016
1	sepantroniumIBA 04/2016
1	Nicotine FDA Link 01/2016
1	Collagen Type I (Type I Collagen)IBA 01/2016
1	Methotrexate (Mexate)FDA LinkGeneric 04/2014
1	VimentinIBA 04/2014

Therapy/Procedure

4	Therapeutics 04/2021 - 01/2007
2	Lymph Node Excision (Lymph Node Dissection) 04/2021 - 03/2019
2	Hysterectomy 03/2019 - 10/2017
2	Drug Therapy (Chemotherapy) 11/2018 - 11/2017
1	First Aid (Aids, First) 01/2021
1	Gastrectomy 11/2017
1	Organ Transplantation 08/2016